Thanks yote.
I copied this from an article:
Activated Carbon:
It has been suggested that activated carbon might play a role in MHLLE (Frakes, 1988; Hemdal, 2003; Hemdal, pers. comm. and Michael, 2003), although the exact mechanism that these various authors suggest differs. Some have theorized that the activated carbon in the aquarium's filtration system could remove necessary trace elements that the fish require. Others hypothesize that activated carbon could leach something into the water that negatively affects the fish. And still others speculate that carbon dust may act as an irritant to the fish.
As additional "anecdotal support" for this theory, Scott Michael noted that a local fish store he visited that used activated carbon was experiencing MHLLE in almost every fish under its care. And I must say, I too have witnessed similar experiences at retail locations that use a lot of activated carbon and then coincidentally experience massive outbreaks of MHLLE. But this is anecdote, not proof. In these situations there was simply no evidence of what might have happed in the absence of activated carbon, all other things remaining equal. It could just as easily be a dietary concern. Or, perhaps the store was using activated carbon to make up for a lack of water changes or other poor husbandry issues. There are simply too many factors involved to point to a definitive cause.
Additionally, activated carbon is used so frequently in the ornamental fish industry and hobby that it is no surprise some fish exposed to activated carbon develop MHLLE. Also, since large numbers of fish routinely housed in systems utilizing activated carbon don't develop MHLLE, and consequently some fish develop MHLLE while not exposed to activated carbon, additional factors must be playing a role in those cases in which fish do exhibit symptoms of MHLLE.